Numerous magazines and artists in other bands have criticised the band openly in the media, amongst them is Marilyn Manson; he wrote the song "Mutilation is the Most Sincere Form of Flattery" as an attack on the band for his Eat Me, Drink Me release. Stating in an interview that "I'm embarrassed to be me because these people are doing a really sad, pitiful, shallow version of what I've done". In response to this, Gerard Way claimed nothing Manson could say would bring the band down. Later on 2007 KoRn described My Chemical Romance as a Gay Ass Emo Band.

Daily Mail published a story entitled "Emo Cult Warning for Parents", in which the reporter warned that emo is a "dangerous teenage cult" and that emo kids "exchange competitive messages on their teenage websites about the scars on their wrists and how best to display them." One of the evil emo bands they called out was MCR. Gerard Way says the story is wrong and they respect everyone.
"In the U.K., there's a conservative newspaper and they refer to us basically as a death cult that encourage kids to self-harm [themselves]," Way blasted. "It was the most ignorant, ridiculous thing we've ever read. We're intelligent and we have something to say. We don't use -for example- God or religion as a scapegoat in a lot of ways bands will to sell a record. We have a lot of respect for everybody and what they believe in."

My Chemical Romance's music has been described by the media as "pop punk", "emo", "alternative rock", "post-hardcore" and "punk revival". The band themselves described their music as simply "rock" or "violent, dangerous pop" on their official website, as well as rejecting the term "emo" to describe their style. Frontman Gerard Way has recently stated in an interview that they were never Emo, as he says emo is "a pile of shit."

One thing is for sure: people want to organize their enviroment. Everything has to be split in to categories or everyone's going to shit themselves. "This is globalization." "This is an emo-kid." "This is parkour." There is no parkour, there is no emo-kids. Non-existing phenomenons are the prime fuel for the media these days. And as the media is ensuing bands that play music that makes everyone confused 'cause "it's not rock or metal but not quite pop, nor anything else" and labelling them as "emo-bands", I am rising against them and have made up a category of my own. It's called unique, and I sure as hell know that's the category My Chemical Romance fits in just perfect.